Biopharmaceutics & Drug Disposition publishes original review articles, short communications, and reports in biopharmaceutics, drug disposition, pharmacokinetics and pharmacodynamics, especially those that have a direct relation to the drug discovery/development and the therapeutic use of drugs.
These include:
? animal and human pharmacological studies that focus on therapeutic response, pharmacodynamics, and toxicity related to plasma and tissue concentrations of drugs and their metabolites
? in vitro and in vivo drug absorption, distribution, metabolism, transport, and excretion studies that facilitate investigations related to the use of drugs in human
? studies on membrane transport and enzymes, including their regulation and the impact of pharmacogenomics on drug absorption and disposition
? simulation and modeling in drug discovery and development
? theoretical treatises
Biopharmaceutics & Drug Disposition刊發(fā)有關生物藥劑學、藥物處置、藥代動力學和藥效學的原創(chuàng)性研究、綜述與簡報，尤其是與藥物研發(fā)和藥物治療相關的文章。感興趣的主題包括：動物和人體藥理學研究，側重于與藥物及其代謝物的血漿和組織濃度相關的治療反應、藥效學和毒性；體外和體內(nèi)藥物吸收、分布、代謝、轉(zhuǎn)運和排泄研究，促進與人類藥物使用相關的研究；關于膜轉(zhuǎn)運和酶的研究，包括其調(diào)控以及藥物基因組學對藥物吸收和處置的影響；藥物發(fā)現(xiàn)和開發(fā)中的模擬和建模等。
